Phenexplain Demonstration

In this example, training was performed on images of red blood cells extracted from thin blood smears sampled from a population of people exposed to malaria. The 200 slides used were diagnose as negative to Malaria by microscopists, meaning no parasites could be found on any of these slides. Nevertheless half of these slides were assessed as positive by qPCR. On original qPCR negative and qPCR positive slides, images displayed variable cell densities with variable background, did not contain any parasites, and did not show any identifiable systematic visible differences. Here, the system enables us to clearly distinguish anemia cells and crenated cells, as well as a bias due to staining. All displayed images are synthetic.

Example 1

qPCR negative
qPCR positive

Example 2

qPCR negative
qPCR positive

Example 3

qPCR negative
qPCR positive

Example 4

qPCR negative
qPCR positive

Example 5

qPCR negative
qPCR positive

Example 6

qPCR negative
qPCR positive

Example 7

qPCR negative
qPCR positive

Example 8

qPCR negative
qPCR positive

Example 9

qPCR negative
qPCR positive

Example 10

qPCR negative
qPCR positive

Example 11

qPCR negative
qPCR positive

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